Driving distance from Burlington, IA to Cape Girardeau, MO is 319 miles (513 km). How far is it from Burlington, IA to Cape Girardeau, MO? It's a 05 hours 26 minutes drive by car. Flight distance is approximately 257 miles (413 km) and flight time from Burlington, IA to Cape Girardeau, MO is 30 minutes. Don't forget to check out our "Gas cost calculator" option. It will calculate cost of driving this particular distance. See the map below for the visual display of the upcoming road trip.
To travel the distance from Burlington, IA to Cape Girardeau, MO, please, click on the map to see the route for the journey. "Gas Cost Calculator" tool is to your right. You can always modify it and make the number more applicable for your journey.
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