Distance from Cape Girardeau, MO to Knoxville, TN
Driving distance from Cape Girardeau, MO to Knoxville, TN is 391 miles (628 km). How far is it from Cape Girardeau, MO to Knoxville, TN? It's a 06 hours 12 minutes drive by car. Flight distance is approximately 324 miles (521 km) and flight time from Cape Girardeau, MO to Knoxville, TN is 39 minutes. Don't forget to check out our "Gas cost calculator" option. It will calculate cost of driving this particular distance. See the map below for the visual display of the upcoming road trip.
Check returning route - Distance from Knoxville, TN to Cape Girardeau, MO How far is it from Cape Girardeau, MO to Knoxville, TN?
To travel the distance from Cape Girardeau, MO to Knoxville, TN, please, click on the map to see the route for the journey. "Gas Cost Calculator" tool is to your right. You can always modify it and make the number more applicable for your journey.
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