Driving distance from Charleston, SC to Cape Girardeau, MO is 758 miles (1220 km). How far is it from Charleston, SC to Cape Girardeau, MO? It's a 12 hours 41 minutes drive by car. Flight distance is approximately 626 miles (1007 km) and flight time from Charleston, SC to Cape Girardeau, MO is 01 hours 15 minutes. Don't forget to check out our "Gas cost calculator" option. It will calculate cost of driving this particular distance. See the map below for the visual display of the upcoming road trip.
To travel the distance from Charleston, SC to Cape Girardeau, MO, please, click on the map to see the route for the journey. "Gas Cost Calculator" tool is to your right. You can always modify it and make the number more applicable for your journey.
Choose a place to stay while traveling from Charleston, SC to Cape Girardeau, MO. We also offer Car Rental widget for your particular journey. There are lots of options to choose from. Give it a try.
Link for your blog / website
Link to share via messenger