Driving distance from Dayton, OH to Cape Girardeau, MO is 421 miles (677 km). How far is it from Dayton, OH to Cape Girardeau, MO? It's a 06 hours 47 minutes drive by car. Flight distance is approximately 334 miles (538 km) and flight time from Dayton, OH to Cape Girardeau, MO is 40 minutes. Don't forget to check out our "Gas cost calculator" option. It will calculate cost of driving this particular distance. See the map below for the visual display of the upcoming road trip.
To travel the distance from Dayton, OH to Cape Girardeau, MO, please, click on the map to see the route for the journey. "Gas Cost Calculator" tool is to your right. You can always modify it and make the number more applicable for your journey.
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