Distance from Des Moines, IA to Saint Charles, MO

Driving distance from Des Moines, IA to Saint Charles, MO is 329 miles (529 km). How far is it from Des Moines, IA to Saint Charles, MO? It's a 05 hours 45 minutes drive by car. Flight distance is approximately 253 miles (407 km) and flight time from Des Moines, IA to Saint Charles, MO is 30 minutes. Don't forget to check out our "Gas cost calculator" option. It will calculate cost of driving this particular distance. See the map below for the visual display of the upcoming road trip.

Driving distance
329 Miles
/
529 Km
Driving distance
Gas consumption
13.16 Gallons
50.26 Litres
Gas consumption
Flight distance
253 Miles
/
407 Km
Flight distance

How far is it from Des Moines, IA to Saint Charles, MO?

To travel the distance from Des Moines, IA to Saint Charles, MO, please, click on the map to see the route for the journey. "Gas Cost Calculator" tool is to your right. You can always modify it and make the number more applicable for your journey.

Book a Hotel for your trip to Saint Charles, MO

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Last distance calculations