Distance from Des Moines, IA to Saint Louis, MO

Driving distance from Des Moines, IA to Saint Louis, MO is 348 miles (560 km). How far is it from Des Moines, IA to Saint Louis, MO? It's a 06 hours 08 minutes drive by car. Flight distance is approximately 271 miles (436 km) and flight time from Des Moines, IA to Saint Louis, MO is 32 minutes. Don't forget to check out our "Gas cost calculator" option. It will calculate cost of driving this particular distance. See the map below for the visual display of the upcoming road trip.

Driving distance
348 Miles
/
560 Km
Driving distance
Gas consumption
13.92 Gallons
53.20 Litres
Gas consumption
Flight distance
271 Miles
/
436 Km
Flight distance

How far is it from Des Moines, IA to Saint Louis, MO?

To travel the distance from Des Moines, IA to Saint Louis, MO, please, click on the map to see the route for the journey. "Gas Cost Calculator" tool is to your right. You can always modify it and make the number more applicable for your journey.

Book a Hotel for your trip to Saint Louis, MO

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Last distance calculations