Distance from Greenville, SC to Lake City, FL
Driving distance from Greenville, SC to Lake City, FL is 428 miles (689 km). How far is it from Greenville, SC to Lake City, FL? It's a 06 hours 29 minutes drive by car. Flight distance is approximately 322 miles (519 km) and flight time from Greenville, SC to Lake City, FL is 38 minutes. Don't forget to check out our "Gas cost calculator" option. It will calculate cost of driving this particular distance. See the map below for the visual display of the upcoming road trip.
Check returning route - Distance from Lake City, FL to Greenville, SC How far is it from Greenville, SC to Lake City, FL?
To travel the distance from Greenville, SC to Lake City, FL, please, click on the map to see the route for the journey. "Gas Cost Calculator" tool is to your right. You can always modify it and make the number more applicable for your journey.
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