Driving distance from Harrisburg, PA to Mount Pleasant, SC is 648 miles (1043 km). How far is it from Harrisburg, PA to Mount Pleasant, SC? It's a 10 hours 03 minutes drive by car. Flight distance is approximately 539 miles (868 km) and flight time from Harrisburg, PA to Mount Pleasant, SC is 01 hours 05 minutes. Don't forget to check out our "Gas cost calculator" option. It will calculate cost of driving this particular distance. See the map below for the visual display of the upcoming road trip.
To travel the distance from Harrisburg, PA to Mount Pleasant, SC, please, click on the map to see the route for the journey. "Gas Cost Calculator" tool is to your right. You can always modify it and make the number more applicable for your journey.
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