Driving distance from Irvine, CA to Palo Alto, CA is 402 miles (648 km). How far is it from Irvine, CA to Palo Alto, CA? It's a 06 hours 44 minutes drive by car. Flight distance is approximately 355 miles (572 km) and flight time from Irvine, CA to Palo Alto, CA is 42 minutes. Don't forget to check out our "Gas cost calculator" option. It will calculate cost of driving this particular distance. See the map below for the visual display of the upcoming road trip.
To travel the distance from Irvine, CA to Palo Alto, CA, please, click on the map to see the route for the journey. "Gas Cost Calculator" tool is to your right. You can always modify it and make the number more applicable for your journey.
Choose a place to stay while traveling from Irvine, CA to Palo Alto, CA. We also offer Car Rental widget for your particular journey. There are lots of options to choose from. Give it a try.
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