Distance from Knoxville, TN to Lake City, FL
Driving distance from Knoxville, TN to Lake City, FL is 501 miles (806 km). How far is it from Knoxville, TN to Lake City, FL? It's a 07 hours 34 minutes drive by car. Flight distance is approximately 406 miles (653 km) and flight time from Knoxville, TN to Lake City, FL is 48 minutes. Don't forget to check out our "Gas cost calculator" option. It will calculate cost of driving this particular distance. See the map below for the visual display of the upcoming road trip.
Check returning route - Distance from Lake City, FL to Knoxville, TN How far is it from Knoxville, TN to Lake City, FL?
To travel the distance from Knoxville, TN to Lake City, FL, please, click on the map to see the route for the journey. "Gas Cost Calculator" tool is to your right. You can always modify it and make the number more applicable for your journey.
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