Driving distance from Knoxville, TN to Mount Pleasant, SC is 378 miles (608 km). How far is it from Knoxville, TN to Mount Pleasant, SC? It's a 05 hours 50 minutes drive by car. Flight distance is approximately 318 miles (512 km) and flight time from Knoxville, TN to Mount Pleasant, SC is 38 minutes. Don't forget to check out our "Gas cost calculator" option. It will calculate cost of driving this particular distance. See the map below for the visual display of the upcoming road trip.
To travel the distance from Knoxville, TN to Mount Pleasant, SC, please, click on the map to see the route for the journey. "Gas Cost Calculator" tool is to your right. You can always modify it and make the number more applicable for your journey.
Choose a place to stay while traveling from Knoxville, TN to Mount Pleasant, SC. We also offer Car Rental widget for your particular journey. There are lots of options to choose from. Give it a try.
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