Distance from Knoxville, TN to Saint Louis, MO

Driving distance from Knoxville, TN to Saint Louis, MO is 489 miles (788 km). How far is it from Knoxville, TN to Saint Louis, MO? It's a 07 hours 51 minutes drive by car. Flight distance is approximately 394 miles (633 km) and flight time from Knoxville, TN to Saint Louis, MO is 47 minutes. Don't forget to check out our "Gas cost calculator" option. It will calculate cost of driving this particular distance. See the map below for the visual display of the upcoming road trip.

Driving distance
489 Miles
/
788 Km
Driving distance
Gas consumption
19.56 Gallons
74.86 Litres
Gas consumption
Flight distance
394 Miles
/
633 Km
Flight distance

How far is it from Knoxville, TN to Saint Louis, MO?

To travel the distance from Knoxville, TN to Saint Louis, MO, please, click on the map to see the route for the journey. "Gas Cost Calculator" tool is to your right. You can always modify it and make the number more applicable for your journey.

Book a Hotel for your trip to Saint Louis, MO

Choose a place to stay while traveling from Knoxville, TN to Saint Louis, MO. We also offer Car Rental widget for your particular journey. There are lots of options to choose from. Give it a try.

Last distance calculations