Driving distance from Lexington, KY to Cape Girardeau, MO is 333 miles (535 km). How far is it from Lexington, KY to Cape Girardeau, MO? It's a 05 hours 23 minutes drive by car. Flight distance is approximately 279 miles (449 km) and flight time from Lexington, KY to Cape Girardeau, MO is 33 minutes. Don't forget to check out our "Gas cost calculator" option. It will calculate cost of driving this particular distance. See the map below for the visual display of the upcoming road trip.
To travel the distance from Lexington, KY to Cape Girardeau, MO, please, click on the map to see the route for the journey. "Gas Cost Calculator" tool is to your right. You can always modify it and make the number more applicable for your journey.
Choose a place to stay while traveling from Lexington, KY to Cape Girardeau, MO. We also offer Car Rental widget for your particular journey. There are lots of options to choose from. Give it a try.
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