Driving distance from Milwaukee, WI to St. Charles, MO is 396 miles (637 km). How far is it from Milwaukee, WI to St. Charles, MO? It's a 06 hours 28 minutes drive by car. Flight distance is approximately 323 miles (520 km) and flight time from Milwaukee, WI to St. Charles, MO is 39 minutes. Don't forget to check out our "Gas cost calculator" option. It will calculate cost of driving this particular distance. See the map below for the visual display of the upcoming road trip.
To travel the distance from Milwaukee, WI to St. Charles, MO, please, click on the map to see the route for the journey. "Gas Cost Calculator" tool is to your right. You can always modify it and make the number more applicable for your journey.
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