Distance from Orlando, FL to Florence, SC

Driving distance from Orlando, FL to Florence, SC is 448 miles (721 km). How far is it from Orlando, FL to Florence, SC? It's a 06 hours 38 minutes drive by car. Flight distance is approximately 402 miles (647 km) and flight time from Orlando, FL to Florence, SC is 48 minutes. Don't forget to check out our "Gas cost calculator" option. It will calculate cost of driving this particular distance. See the map below for the visual display of the upcoming road trip.

Driving distance
448 Miles
/
721 Km
Driving distance
Gas consumption
17.92 Gallons
68.50 Litres
Gas consumption
Flight distance
402 Miles
/
647 Km
Flight distance

How far is it from Orlando, FL to Florence, SC?

To travel the distance from Orlando, FL to Florence, SC, please, click on the map to see the route for the journey. "Gas Cost Calculator" tool is to your right. You can always modify it and make the number more applicable for your journey.

Book a Hotel for your trip to Florence, SC

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