Driving distance from Port St. Lucie, FL to Myrtle Beach, SC is 601 miles (967 km). How far is it from Port St. Lucie, FL to Myrtle Beach, SC? It's a 09 hours 19 minutes drive by car. Flight distance is approximately 452 miles (727 km) and flight time from Port St. Lucie, FL to Myrtle Beach, SC is 54 minutes. Don't forget to check out our "Gas cost calculator" option. It will calculate cost of driving this particular distance. See the map below for the visual display of the upcoming road trip.
To travel the distance from Port St. Lucie, FL to Myrtle Beach, SC, please, click on the map to see the route for the journey. "Gas Cost Calculator" tool is to your right. You can always modify it and make the number more applicable for your journey.
Choose a place to stay while traveling from Port St. Lucie, FL to Myrtle Beach, SC. We also offer Car Rental widget for your particular journey. There are lots of options to choose from. Give it a try.
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