Driving distance from St. Joseph, MO to Cape Girardeau, MO is 404 miles (651 km). How far is it from St. Joseph, MO to Cape Girardeau, MO? It's a 06 hours 34 minutes drive by car. Flight distance is approximately 334 miles (538 km) and flight time from St. Joseph, MO to Cape Girardeau, MO is 40 minutes. Don't forget to check out our "Gas cost calculator" option. It will calculate cost of driving this particular distance. See the map below for the visual display of the upcoming road trip.
To travel the distance from St. Joseph, MO to Cape Girardeau, MO, please, click on the map to see the route for the journey. "Gas Cost Calculator" tool is to your right. You can always modify it and make the number more applicable for your journey.
Choose a place to stay while traveling from St. Joseph, MO to Cape Girardeau, MO. We also offer Car Rental widget for your particular journey. There are lots of options to choose from. Give it a try.
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