Distance from St. Louis, MO to Des Moines, IA

Driving distance from St. Louis, MO to Des Moines, IA is 350 miles (563 km). How far is it from St. Louis, MO to Des Moines, IA? It's a 05 hours 33 minutes drive by car. Flight distance is approximately 273 miles (439 km) and flight time from St. Louis, MO to Des Moines, IA is 32 minutes. Don't forget to check out our "Gas cost calculator" option. It will calculate cost of driving this particular distance. See the map below for the visual display of the upcoming road trip.

Driving distance
350 Miles
/
563 Km
Driving distance
Gas consumption
14.00 Gallons
53.49 Litres
Gas consumption
Flight distance
273 Miles
/
439 Km
Flight distance

How far is it from St. Louis, MO to Des Moines, IA?

To travel the distance from St. Louis, MO to Des Moines, IA, please, click on the map to see the route for the journey. "Gas Cost Calculator" tool is to your right. You can always modify it and make the number more applicable for your journey.

Book a Hotel for your trip to Des Moines, IA

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Last distance calculations