Driving distance from St. Louis, MO to Sioux City, IA is 525 miles (845 km). How far is it from St. Louis, MO to Sioux City, IA? It's a 08 hours 15 minutes drive by car. Flight distance is approximately 421 miles (678 km) and flight time from St. Louis, MO to Sioux City, IA is 50 minutes. Don't forget to check out our "Gas cost calculator" option. It will calculate cost of driving this particular distance. See the map below for the visual display of the upcoming road trip.
To travel the distance from St. Louis, MO to Sioux City, IA, please, click on the map to see the route for the journey. "Gas Cost Calculator" tool is to your right. You can always modify it and make the number more applicable for your journey.
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