Driving distance from Tupelo, MS to Florence, SC is 572 miles (921 km). How far is it from Tupelo, MS to Florence, SC? It's a 08 hours 46 minutes drive by car. Flight distance is approximately 511 miles (822 km) and flight time from Tupelo, MS to Florence, SC is 01 hours 01 minutes. Don't forget to check out our "Gas cost calculator" option. It will calculate cost of driving this particular distance. See the map below for the visual display of the upcoming road trip.
To travel the distance from Tupelo, MS to Florence, SC, please, click on the map to see the route for the journey. "Gas Cost Calculator" tool is to your right. You can always modify it and make the number more applicable for your journey.
Choose a place to stay while traveling from Tupelo, MS to Florence, SC. We also offer Car Rental widget for your particular journey. There are lots of options to choose from. Give it a try.
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