Distance from Tupelo, MS to Greenville, SC

Driving distance from Tupelo, MS to Greenville, SC is 428 miles (688 km). How far is it from Tupelo, MS to Greenville, SC? It's a 06 hours 33 minutes drive by car. Flight distance is approximately 361 miles (581 km) and flight time from Tupelo, MS to Greenville, SC is 43 minutes. Don't forget to check out our "Gas cost calculator" option. It will calculate cost of driving this particular distance. See the map below for the visual display of the upcoming road trip.

Driving distance
428 Miles
/
688 Km
Driving distance
Gas consumption
17.12 Gallons
65.36 Litres
Gas consumption
Flight distance
361 Miles
/
581 Km
Flight distance

How far is it from Tupelo, MS to Greenville, SC?

To travel the distance from Tupelo, MS to Greenville, SC, please, click on the map to see the route for the journey. "Gas Cost Calculator" tool is to your right. You can always modify it and make the number more applicable for your journey.

Book a Hotel for your trip to Greenville, SC

Choose a place to stay while traveling from Tupelo, MS to Greenville, SC. We also offer Car Rental widget for your particular journey. There are lots of options to choose from. Give it a try.

Last distance calculations