Distance from Tupelo, MS to Knoxville, TN

Driving distance from Tupelo, MS to Knoxville, TN is 355 miles (571 km). How far is it from Tupelo, MS to Knoxville, TN? It's a 05 hours 45 minutes drive by car. Flight distance is approximately 295 miles (474 km) and flight time from Tupelo, MS to Knoxville, TN is 35 minutes. Don't forget to check out our "Gas cost calculator" option. It will calculate cost of driving this particular distance. See the map below for the visual display of the upcoming road trip.

Driving distance
355 Miles
/
571 Km
Driving distance
Gas consumption
14.20 Gallons
54.25 Litres
Gas consumption
Flight distance
295 Miles
/
474 Km
Flight distance

How far is it from Tupelo, MS to Knoxville, TN?

To travel the distance from Tupelo, MS to Knoxville, TN, please, click on the map to see the route for the journey. "Gas Cost Calculator" tool is to your right. You can always modify it and make the number more applicable for your journey.

Book a Hotel for your trip to Knoxville, TN

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Last distance calculations